Computational Analysis of Damaging Single-Nucleotide Polymorphisms and Their Structural and Functional Impact on the Insulin Receptor

Single-nucleotide polymorphisms (SNPs) associated with complex disorders can create, destroy, or modify protein coding sites. Single amino acid substitutions in the insulin receptor (INSR) are the most common forms of genetic variations that account for various diseases like Donohue syndrome or Lepr...

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Dades bibliogràfiques
Publicat a:Biomed Res Int
Autors principals: Mahmud, Zabed, Malik, Syeda Umme Fahmida, Ahmed, Jahed, Azad, Abul Kalam
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093252/
https://ncbi.nlm.nih.gov/pubmed/27840822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2023803
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