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Human Norovirus Aptamer Exhibits High Degree of Target Conformation-Dependent Binding Similar to That of Receptors and Discriminates Particle Functionality

Although two in vitro cultivation methods have been reported, discrimination of infectious human norovirus particles for study of viral inactivation is still a challenge, as both rely on reverse transcriptase quantitative PCR. Histo-blood group antigen (HBGA) binding assays serve as a proxy for esti...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Moore, Matthew D., Bobay, Benjamin G., Mertens, Brittany, Jaykus, Lee-Ann
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093151/
https://ncbi.nlm.nih.gov/pubmed/27830193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00298-16
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