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Free radical-derived quinone methide mediates skin tumor promotion by butylated hydroxytoluene hydroperoxide: expanded role for electrophiles in multistage carcinogenesis.

Free radical derivatives of peroxides, hydroperoxides, and anthrones are thought to mediate tumor promotion by these compounds. Further, the promoting activity of phorbol esters is attributed, in part, to their ability to stimulate the cellular generation of oxygen radicals. A hydroperoxide metaboli...

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Detalhes bibliográficos
Main Authors: Guyton, K Z, Bhan, P, Kuppusamy, P, Zweier, J L, Trush, M A, Kensler, T W
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC50931/
https://ncbi.nlm.nih.gov/pubmed/1846971
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