Spontaneous Autoimmunity in 129 and C57BL/6 Mice—Implications for Autoimmunity Described in Gene-Targeted Mice

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder in which complex genetic factors play an important role. Several strains of gene-targeted mice have been reported to develop SLE, implicating the null genes in the causation of disease. However, hybrid strains between 129 and C5...

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Detalhes bibliográficos

Publicado no:	PLoS Biol
Principais autores:	Bygrave, Anne E, Rose, Kirsten L, Cortes-Hernandez, Josefina, Warren, Joanna, Rigby, Robert J, Cook, H. Terence, Walport, Mark J, Vyse, Timothy J, Botto, Marina
Formato:	Artigo
Idioma:	Inglês
Publicado em:	PLOS 2004
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC509305/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15314659/ https://ncbi.nlm.nih.govhttps://doi.org/10.1371/journal.pbio.0020243
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