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Generation of a Humanized Mouse Liver Using Human Hepatic Stem Cells

A novel animal model involving chimeric mice with humanized livers established via human hepatocyte transplantation has been developed. These mice, in which the liver has been repopulated with functional human hepatocytes, could serve as a useful tool for investigating human hepatic cell biology, dr...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Zhang, Ran-Ran, Zheng, Yun-Wen, Taniguchi, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091961/
https://ncbi.nlm.nih.gov/pubmed/27684205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54167
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