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Generation of a Humanized Mouse Liver Using Human Hepatic Stem Cells
A novel animal model involving chimeric mice with humanized livers established via human hepatocyte transplantation has been developed. These mice, in which the liver has been repopulated with functional human hepatocytes, could serve as a useful tool for investigating human hepatic cell biology, dr...
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Publicado no: | J Vis Exp |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MyJove Corporation
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5091961/ https://ncbi.nlm.nih.gov/pubmed/27684205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54167 |
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