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Fosfomycin Addition to Poly((D,L)-Lactide) Coating Does Not Affect Prophylaxis Efficacy in Rat Implant-Related Infection Model, But That of Gentamicin Does

Gentamicin is the preferred antimicrobial agent used in implant coating for the prevention of implant-related infections (IRI). However, the present heavy local and systemic administration of gentamicin can lead to increased resistance, which has made its future use uncertain, together with related...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gulcu, Anil, Akman, Alp, Demirkan, Ahmet Fahir, Yorukoglu, Ali Cagdas, Kaleli, Ilknur, Bir, Ferda
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091905/
https://ncbi.nlm.nih.gov/pubmed/27806071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165544
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