Antiretroviral Drug Activity in Macaques Infected during Pre-Exposure Prophylaxis Has a Transient Effect on Cell-Associated SHIV DNA Reservoirs

BACKGROUND: Pre-exposure prophylaxis (PrEP) with emtricitabine and tenofovir disoproxil fumarate (FTC/TDF) is a novel HIV prevention strategy. Suboptimal PrEP adherence and HIV infection creates an opportunity for continued antiretroviral drug activity during undiagnosed infection. We previously sho...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Cong, Mian-er, Pau, Chou-Pong, Heneine, Walid, García-Lerma, J. Gerardo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091888/
https://ncbi.nlm.nih.gov/pubmed/27806064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164821
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