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Design, Synthesis, and In Vitro and In Vivo Evaluation of an (18)F-Labeled Sphingosine 1-Phosphate Receptor 1 (S1P(1)) PET Tracer
Sphingosine 1-phosphate receptor 1 (S1P(1)) plays a pivotal signaling role in inflammatory response; because S1P(1) modulation has been identified as a therapeutic target for various diseases, a PET tracer for S1P(1) would be a useful tool. Fourteen fluorine-containing analogues of S1P ligands were...
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| Publicado no: | J Med Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5091660/ https://ncbi.nlm.nih.gov/pubmed/27280499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.6b00390 |
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