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Design, Synthesis, and In Vitro and In Vivo Evaluation of an (18)F-Labeled Sphingosine 1-Phosphate Receptor 1 (S1P(1)) PET Tracer

Sphingosine 1-phosphate receptor 1 (S1P(1)) plays a pivotal signaling role in inflammatory response; because S1P(1) modulation has been identified as a therapeutic target for various diseases, a PET tracer for S1P(1) would be a useful tool. Fourteen fluorine-containing analogues of S1P ligands were...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Med Chem
मुख्य लेखकों: Rosenberg, Adam J., Liu, Hui, Jin, Hongjun, Yue, Xuyi, Riley, Sean, Brown, Steven J., Tu, Zhude
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091660/
https://ncbi.nlm.nih.gov/pubmed/27280499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.6b00390
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