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MT(1) and MT(2) Melatonin Receptors: A Therapeutic Perspective

Melatonin, or 5-methoxy-N-acetyltryptamine, is synthesized and released by the pineal gland and locally in the retina following a circadian rhythm, with low levels during the day and elevated levels at night. Melatonin activates two high-affinity G protein–coupled receptors, termed MT(1) and MT(2),...

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Detalhes bibliográficos
Publicado no:Annu Rev Pharmacol Toxicol
Main Authors: Liu, Jiabei, Clough, Shannon J., Hutchinson, Anthony J., Adamah-Biassi, Ekue B., Popovska-Gorevski, Marina, Dubocovich, Margarita L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091650/
https://ncbi.nlm.nih.gov/pubmed/26514204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010814-124742
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