HIV-1 kills renal tubular epithelial cells in vitro by triggering an apoptotic pathway involving caspase activation and Fas upregulation.

HIV-infected patients suffer several renal syndromes, which can progress rapidly from renal insufficiency to end-stage renal disease. Histologically, HIV-induced nephropathy is characterized by prominent tubulopathy with apoptosis of tubular cells. Clinical and experimental evidence suggests that re...

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Библиографические подробности
Главные авторы: Conaldi, P G, Biancone, L, Bottelli, A, Wade-Evans, A, Racusen, L C, Boccellino, M, Orlandi, V, Serra, C, Camussi, G, Toniolo, A
Формат: Artigo
Язык:Inglês
Опубликовано: 1998
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC509158/
https://ncbi.nlm.nih.gov/pubmed/9854039
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