GM-CSF transgene expression in the airway allows aerosolized ovalbumin to induce allergic sensitization in mice.

The purpose of this study was to explore whether repeated exposure to aerosolized ovalbumin (OVA) in the context of local expression of GM-CSF can initiate a Th2-driven, eosinophilic inflammation in the airways. On day -1, Balb/c mice were infected intranasally with an adenovirus construct expressin...

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Detalhes bibliográficos
Main Authors: Stämpfli, M R, Wiley, R E, Neigh, G S, Gajewska, B U, Lei, X F, Snider, D P, Xing, Z, Jordana, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC509118/
https://ncbi.nlm.nih.gov/pubmed/9802884
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