Integrin-dependent homotypic adhesion of neutrophils. Arachidonic acid activates Raf-1/Mek/Erk via a 5-lipoxygenase- dependent pathway.

AA stimulates integrin-dependent neutrophil adhesion, a critical early step in acute inflammation. However, neither the signaling pathway(s) of AA-stimulated adhesion, nor whether AA acts directly or through the generation of active metabolites, has been elucidated. Previously, we have observed a ti...

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Bibliographic Details

Published in:	J Clin Invest
Main Authors:	Capodici, C, Pillinger, M H, Han, G, Philips, M R, Weissmann, G
Format:	Artigo
Language:	Inglês
Published:	American Society for Clinical Investigation 1998
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC509078/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9649570/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI592
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