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2‐Hydoxyglutarate: D/Riving Pathology in gLiomaS
Common pathways and mechanisms can be found in both cancers and inborn errors of metabolism. 2‐Hydroxyglutarate (2‐HG) acidurias and isocitrate dehydrogenase (IDH) 1/2 mutant tumors are examples of this phenomenon. 2‐HG can exist in two chiral forms, D(R)‐2‐HG and L(S)‐2‐HG, which are elevated in D‐...
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| Gepubliceerd in: | Brain Pathol |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley and Sons Inc.
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5090714/ https://ncbi.nlm.nih.gov/pubmed/26526944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12309 |
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