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Targeted amplification of delivery to cell surface receptors by dendrimer self-assembly

Nanometer-scale architectures assembled on cell surface receptors from smaller macromolecular constituents generated a large amplification of fluorescence. A targeted dendrimer was synthesized from a cystamine-core G4 PAMAM dendrimer, and contained an anti-BrE3 monoclonal antibody as the targeting g...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Bioorg Med Chem Lett
Hauptverfasser: Isaacman, Steven, Buckley, Michael, Wang, Xiaojian, Wang, Edwin Y., Liebes, Leonard, Canary, James W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5090713/
https://ncbi.nlm.nih.gov/pubmed/24513050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.01.063
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