Exacerbation of antigen-induced arthritis in urokinase-deficient mice.

In rheumatoid arthritis, synovial expression of urokinase (uPA) activity is greatly increased (Busso, N., V. Péclat, A. So, and A. -P. Sappino. 1997. Ann. Rheum. Dis. 56:550- 557). We report the same effect in murine antigen-induced arthritis. uPA-mediated plasminogen activation in arthritic joints...

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Main Authors: Busso, N, Péclat, V, Van Ness, K, Kolodziesczyk, E, Degen, J, Bugge, T, So, A
Format: Artigo
Sprog:Inglês
Udgivet: 1998
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC509063/
https://ncbi.nlm.nih.gov/pubmed/9649555
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