Tumour microenvironment-responsive lipoic acid nanoparticles for targeted delivery of docetaxel to lung cancer

In the present study, we developed a novel type of reduction-sensitive nanoparticles (NPs) for docetaxel (DTX) delivery based on cross-linked lipoic acid NPs (LANPs). The physicochemical properties, cellular uptake and in vitro cytotoxicity of DTX loaded LANPs (DTX-LANPs) on A549 cells were investig...

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Vydáno v:Sci Rep
Hlavní autoři: Gu, Fenfen, Hu, Chuling, Tai, Zhongguang, Yao, Chong, Tian, Jing, Zhang, Lijuan, Xia, Qingming, Gong, Chunai, Gao, Yuan, Gao, Shen
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5090365/
https://ncbi.nlm.nih.gov/pubmed/27805051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36281
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