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AGEs Induced Autophagy Impairs Cutaneous Wound Healing via Stimulating Macrophage Polarization to M1 in Diabetes

Autophagy is essential in physiological and pathological processes, however, the role of autophagy in cutaneous wound healing and the underlying molecular mechanism remain elusive. We hypothesized that autophagy plays an important role in regulating wound healing. Here, we show that enhanced autopha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Guo, Yuanyuan, Lin, Cai, Xu, Peng, Wu, Shan, Fu, Xiujun, Xia, Weidong, Yao, Min
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5090347/
https://ncbi.nlm.nih.gov/pubmed/27805071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36416
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