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A Golgi rhomboid protease Rbd2 recruits Cdc48 to cleave yeast SREBP

Hypoxic growth of fungi requires sterol regulatory element‐binding protein (SREBP) transcription factors, and human opportunistic fungal pathogens require SREBP activation for virulence. Proteolytic release of fission yeast SREBPs from the membrane in response to low oxygen requires the Golgi membra...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Hwang, Jiwon, Ribbens, Diedre, Raychaudhuri, Sumana, Cairns, Leah, Gu, He, Frost, Adam, Urban, Siniša, Espenshade, Peter J
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5090219/
https://ncbi.nlm.nih.gov/pubmed/27655872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201693923
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