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Regulation of RNA-binding proteins affinity to export receptors enables the nuclear basket proteins to distinguish and retain aberrant mRNAs

Export of messenger ribonucleic acids (mRNAs) into the cytoplasm is a fundamental step in gene regulation processes, which is meticulously quality controlled by highly efficient mechanisms in eukaryotic cells. Yet, it remains unclear how the aberrant mRNAs are recognized and retained inside the nucl...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Soheilypour, M., Mofrad, M. R. K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5090210/
https://ncbi.nlm.nih.gov/pubmed/27805000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35380
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