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Cardiac fibroblasts are predisposed to convert into myocyte phenotype: specific effect of transforming growth factor beta.

Cardiac fibroblasts are mainly responsible for the synthesis of major extracellular matrix proteins in the heart, including fibrillar collagen types I and III and fibronectin. In this report we show that these cells, when stimulated by transforming growth factor beta 1 (TGF-beta 1), acquire certain...

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Autori principali: Eghbali, M, Tomek, R, Woods, C, Bhambi, B
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1991
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC50900/
https://ncbi.nlm.nih.gov/pubmed/1704132
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