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Cardiac fibroblasts are predisposed to convert into myocyte phenotype: specific effect of transforming growth factor beta.

Cardiac fibroblasts are mainly responsible for the synthesis of major extracellular matrix proteins in the heart, including fibrillar collagen types I and III and fibronectin. In this report we show that these cells, when stimulated by transforming growth factor beta 1 (TGF-beta 1), acquire certain...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Eghbali, M, Tomek, R, Woods, C, Bhambi, B
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50900/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1704132/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.3.795
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