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The Selenocysteine-Specific Elongation Factor Contains Unique Sequences That Are Required for Both Nuclear Export and Selenocysteine Incorporation

Selenocysteine (Sec) is a critical residue in at least 25 human proteins that are essential for antioxidant defense and redox signaling in cells. Sec is inserted into proteins cotranslationally by the recoding of an in-frame UGA termination codon to a Sec codon. In eukaryotes, this recoding event re...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Dubey, Aditi, Copeland, Paul R.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089774/
https://ncbi.nlm.nih.gov/pubmed/27802322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165642
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