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Safety and efficacy of denosumab in children with osteogenesis imperfecta - a first prospective trial
OBJECTIVES: Osteogenesis imperfecta (OI) is a rare hereditary disease leading to bone fragility. Denosumab as a RANK ligand antibody inhibiting osteoclast maturation has been approved for osteoporosis treatment in adults. Aim of this study was a 48-week, open-label, pilot study of the safety and eff...
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| Publicado no: | J Musculoskelet Neuronal Interact |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Society of Musculoskeletal and Neuronal Interactions
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5089451/ https://ncbi.nlm.nih.gov/pubmed/26944820 |
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