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Resistance to adenovirally induced hyperleptinemia in rats. Comparison of ventromedial hypothalamic lesions and mutated leptin receptors.

Leptin regulates appetite and body weight via hypothalamic targets, but it can act directly on cultured pancreatic islets to regulate their fat metabolism. To obtain in vivo evidence that leptin may act peripherally as well as centrally, we compared the effect of adenovirally induced hyperleptinemia...

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Bibliographic Details
Main Authors: Koyama, K, Shimabukuro, M, Chen, G, Wang, M Y, Lee, Y, Kalra, P S, Dube, M G, Kalra, S P, Newgard, C B, Unger, R H
Format: Artigo
Language:Inglês
Published: 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC508935/
https://ncbi.nlm.nih.gov/pubmed/9710441
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