Immunomodulation by mucosal gene transfer using TGF-beta DNA.

This report evaluates the efficacy of DNA encoding TGF-beta administered mucosally to suppress immunity and modulate the immunoinflammatory response to herpes simplex virus (HSV) infection. A single intranasal administration of an eukaryotic expression vector encoding TGF-beta1 led to expression in...

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Bibliographic Details
Main Authors: Kuklin, N A, Daheshia, M, Chun, S, Rouse, B T
Format: Artigo
Language:Inglês
Published: 1998
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC508903/
https://ncbi.nlm.nih.gov/pubmed/9664086
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