Dysfunction of endothelial progenitor cells is associated with the type I IFN pathway in patients with polymyositis and dermatomyositis

Objective. Alterations in phenotype and function of endothelial progenitor cells (EPCs) have been associated with poor vascular outcomes and impaired vascular repair in various conditions. Our hypothesis was that patients with PM and DM have dysregulation of EPCs driven by type I IFN and IL-18 simil...

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Detalhes bibliográficos
Publicado no:Rheumatology (Oxford)
Main Authors: Ekholm, Louise, Kahlenberg, J. Michelle, Barbasso Helmers, Sevim, Tjärnlund, Anna, Yalavarthi, Srilakshmi, Zhao, Wenpu, Seto, Nickie, Betteridge, Zoe, Lundberg, Ingrid E., Kaplan, Mariana J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Clinical Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088625/
https://ncbi.nlm.nih.gov/pubmed/27498356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kew288
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