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Spatial focalization of pheromone/MAPK signaling triggers commitment to cell–cell fusion

Cell fusion is universal in eukaryotes for fertilization and development, but what signals this process is unknown. Here, we show in Schizosaccharomyces pombe that fusion does not require a dedicated signal but is triggered by spatial focalization of the same pheromone–GPCR (G-protein-coupled recept...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genes Dev
Hauptverfasser: Dudin, Omaya, Merlini, Laura, Martin, Sophie G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088570/
https://ncbi.nlm.nih.gov/pubmed/27798845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.286922.116
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