Dual Impact of Tolvaptan on Intracellular and Extracellular Water in Chronic Kidney Disease Patients with Fluid Retention

Objective Tolvaptan, an oral selective V2-receptor antagonist, is a water diuretic that ameliorates fluid retention with a lower risk of a worsening renal function than conventional loop diuretics. Although loop diuretics predominantly decrease extracellular water (ECW) compared with intracellular w...

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Pubblicato in:Intern Med
Autori principali: Masuda, Takahiro, Murakami, Takuya, Igarashi, Yusuke, Okabe, Kyochika, Kobayashi, Takahisa, Takeda, Shin-ichi, Saito, Takako, Sekiguchi, Chuji, Miyazawa, Yasuharu, Akimoto, Tetsu, Saito, Osamu, Muto, Shigeaki, Nagata, Daisuke
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Japanese Society of Internal Medicine 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088534/
https://ncbi.nlm.nih.gov/pubmed/27725533
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