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Effects of Thyroxine Exposure on the Twist 1 +/− Phenotype: A Test of Gene-Environment Interaction Modeling for Craniosynostosis

Craniosynostosis, the premature fusion of one or more of the cranial sutures, is estimated to occur in 1:1800-2500 births. Genetic murine models of craniosynostosis exist, but often imperfectly model human patients. Case, cohort, and surveillance studies have identified excess thyroid hormone as an...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Birth Defects Res A Clin Mol Teratol
Prif Awduron: Durham, Emily L., Howie, R. Nicole, Black, Laurel, Bennfors, Grace, Parsons, Trish E., Elsalanty, Mohammed, Yu, Jack C., Weinberg, Seth M., Cray, James J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088492/
https://ncbi.nlm.nih.gov/pubmed/27435288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.23543
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