Evidence for defects in the trafficking and translocation of GLUT4 glucose transporters in skeletal muscle as a cause of human insulin resistance.

Insulin resistance is instrumental in the pathogenesis of type 2 diabetes mellitus and the Insulin Resistance Syndrome. While insulin resistance involves decreased glucose transport activity in skeletal muscle, its molecular basis is unknown. Since muscle GLUT4 glucose transporter levels are normal...

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Detalles Bibliográficos
Main Authors: Garvey, W T, Maianu, L, Zhu, J H, Brechtel-Hook, G, Wallace, P, Baron, A D
Formato: Artigo
Idioma:Inglês
Publicado: 1998
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC508827/
https://ncbi.nlm.nih.gov/pubmed/9616209
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