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Evidence for defects in the trafficking and translocation of GLUT4 glucose transporters in skeletal muscle as a cause of human insulin resistance.

Insulin resistance is instrumental in the pathogenesis of type 2 diabetes mellitus and the Insulin Resistance Syndrome. While insulin resistance involves decreased glucose transport activity in skeletal muscle, its molecular basis is unknown. Since muscle GLUT4 glucose transporter levels are normal...

詳細記述

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書誌詳細
主要な著者: Garvey, W T, Maianu, L, Zhu, J H, Brechtel-Hook, G, Wallace, P, Baron, A D
フォーマット: Artigo
言語:Inglês
出版事項: 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC508827/
https://ncbi.nlm.nih.gov/pubmed/9616209
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