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Eliminating Nox2 reactive oxygen species production protects dystrophic skeletal muscle from pathological calcium influx assessed in vivo by manganese‐enhanced magnetic resonance imaging

KEY POINTS: Inhibiting Nox2 reactive oxygen species (ROS) production reduced in vivo calcium influx in dystrophic muscle. The lack of Nox2 ROS production protected against decreased in vivo muscle function in dystrophic mice. Manganese‐enhanced magnetic resonance imaging (MEMRI) was able to detect a...

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Vydáno v:J Physiol
Hlavní autoři: Loehr, James A., Stinnett, Gary R., Hernández‐Rivera, Mayra, Roten, Wesley T., Wilson, Lon J., Pautler, Robia G., Rodney, George G.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088246/
https://ncbi.nlm.nih.gov/pubmed/27555555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272907
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