Cathepsin S activity regulates antigen presentation and immunity.

MHC class II molecules display antigenic peptides on cell surfaces for recognition by CD4(+) T cells. Proteolysis is required in this process both for degradation of invariant chain (Ii) from class II-Ii complexes to allow subsequent binding of peptides, and for generation of the antigenic peptides....

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Bibliografische gegevens
Hoofdauteurs: Riese, R J, Mitchell, R N, Villadangos, J A, Shi, G P, Palmer, J T, Karp, E R, De Sanctis, G T, Ploegh, H L, Chapman, H A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1998
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC508824/
https://ncbi.nlm.nih.gov/pubmed/9616206
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