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An acetylcholine receptor alpha subunit promoter confers intrathymic expression in transgenic mice. Implications for tolerance of a transgenic self-antigen and for autoreactivity in myasthenia gravis.

Myasthenia gravis (MG) is an autoimmune disease targeting the skeletal muscle acetylcholine receptor (AChR). Although the autoantigen is present in the thymus, it is not tolerated in MG patients. In addition, the nature of the cell bearing the autoantigen is controversial. To approach these question...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Salmon, A M, Bruand, C, Cardona, A, Changeux, J P, Berrih-Aknin, S
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1998
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC508823/
https://ncbi.nlm.nih.gov/pubmed/9616205
Tagiau: Ychwanegu Tag
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