GluN2A Subunit-Containing NMDA Receptors Are the Preferential Neuronal Targets of Homocysteine

Homocysteine (HCY) is an endogenous redox active amino acid, best known as contributor to various neurodegenerative disorders. Although it is known that HCY can activate NMDA receptors (NMDARs), the mechanisms of its action on receptors composed of different NMDA receptor subunits remains almost unk...

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Bibliographic Details
Published in:Front Cell Neurosci
Main Authors: Sibarov, Dmitry A., Abushik, Polina A., Giniatullin, Rashid, Antonov, Sergei M.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088185/
https://ncbi.nlm.nih.gov/pubmed/27847466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00246
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