Cytotoxic T cell response against the chimeric p210 BCR-ABL protein in patients with chronic myelogenous leukemia.

Human chronic myelogenous leukemia (CML) is characterized by a translocation between chromosomes 9 and 22 that results in a BCR-ABL fusion gene coding for chimeric proteins. The junctional region of the BCR-ABLb3a2 molecule represents a potential leukemia-specific antigen which could be recognized b...

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Main Authors: Yotnda, P, Firat, H, Garcia-Pons, F, Garcia, Z, Gourru, G, Vernant, J P, Lemonnier, F A, Leblond, V, Langlade-Demoyen, P
Format: Artigo
Sprog:Inglês
Udgivet: 1998
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC508817/
https://ncbi.nlm.nih.gov/pubmed/9593785
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