Impact of Long-Term Proton Pump Inhibitor Therapy on Gut Microbiota in F344 Rats: Pilot Study

BACKGROUND/AIMS: To evaluate changes in gut microbiota composition following long-term proton pump inhibitor (PPI) treatment. METHODS: Twenty-four-week-old F344 rats were fed diets with (n=6) or without (n=5) lansoprazole for 50 weeks. Profiles of luminal microbiota in the terminal ileum were then a...

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Bibliografiske detaljer
Udgivet i:Gut Liver
Main Authors: Shin, Cheol Min, Kim, Nayoung, Kim, Yong Sung, Nam, Ryoung Hee, Park, Ji Hyun, Lee, Dong Ho, Seok, Yeong-Jae, Kim, Yeon-Ran, Kim, Joo-Hyon, Kim, Jung Min, Kim, Joo Sung, Jung, Hyun Chae
Format: Artigo
Sprog:Inglês
Udgivet: Editorial Office of Gut and Liver 2016
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087928/
https://ncbi.nlm.nih.gov/pubmed/27458177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5009/gnl15529
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