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A Novel Physiological Glycosaminoglycan-Deficient Splice Variant of Neuropilin-1 Is Anti-Tumorigenic In Vitro and In Vivo

Neuropilin-1 (NRP1) is a transmembrane protein acting as a co-receptor for several growth factors and interacting with other proteins such as integrins and plexins/semaphorins. It is involved in axonal development, angiogenesis and cancer progression. Its primary mRNA is subjected to alternative spl...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Hendricks, Céline, Dubail, Johanne, Brohée, Laura, Delforge, Yves, Colige, Alain, Deroanne, Christophe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087894/
https://ncbi.nlm.nih.gov/pubmed/27798666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165153
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