Self-assembling peptide nanofibers containing phenylalanine for the controlled release of 5-fluorouracil

The study shows that RADA-F6 peptide with pH-responsive self-assembling nature can be effectively used as a drug delivery system for the sustained release of a potent anticancer drug 5-fluorouracil (5-FU) at basic pH. As 5-FU contains the aromatic pyrimidine ring, RADA-F6 system is suitable for entr...

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Bibliografski detalji
Izdano u:Int J Nanomedicine
Glavni autori: Ashwanikumar, Narayanan, Kumar, Nisha Asok, Saneesh Babu, Padma S, Sivakumar, Krishnankutty C, Vadakkan, Mithun Varghese, Nair, Parvathi, Hema Saranya, Ilamathi, Asha Nair, Sivakumari, Vinod Kumar, Gopalakrishnapillai S
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2016
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087806/
https://ncbi.nlm.nih.gov/pubmed/27822037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S104707
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