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miR-497 suppresses epithelial–mesenchymal transition and metastasis in colorectal cancer cells by targeting fos-related antigen-1

OBJECTIVE: MicroRNAs have key roles in tumor metastasis. The acquisition of metastatic capability by cancer cells is associated with epithelial–mesenchymal transition (EMT). Here, we describe the role and molecular mechanism of miR-497 in colorectal cancer (CRC) cell EMT, migration, and invasion. ME...

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Publicat a:Onco Targets Ther
Autors principals: Zhang, Nan, Shen, Quan, Zhang, Pingping
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087769/
https://ncbi.nlm.nih.gov/pubmed/27822064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S114609
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