MicroRNA-205 Maintains T Cell Development following Stress by Regulating Forkhead Box N1 and Selected Chemokines

The thymus, an organ responsible for T cell development, is one of the more stress-sensitive tissues in the body. Stress, in the form of infections, radiation exposure, and steroids, impairs thymic epithelial cell (TEC) functions and induces the programmed cell death of immature thymocytes. MicroRNA...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Hoover, Ashley R., Dozmorov, Igor, MacLeod, Jessica, Du, Qiumei, de la Morena, M. Teresa, Forbess, Joseph, Guleserian, Kristine, Cleaver, Ondine B., van Oers, Nicolai S. C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087740/
https://ncbi.nlm.nih.gov/pubmed/27646003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.744508
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