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Phospholipase Cβ-TRAX Association Is Required for PC12 Cell Differentiation

When treated with nerve growth factor, PC12 cells will differentiate over the course of several days. Here, we have followed changes during differentiation in the cellular levels of phosphoinositide-specific phospholipase Cβ (PLCβ) and its activator, Gα(q), which together mediate Ca(2+) release. We...

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Pubblicato in:J Biol Chem
Autori principali: Garwain, Osama, Scarlata, Suzanne
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087718/
https://ncbi.nlm.nih.gov/pubmed/27624933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.744953
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