Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate

Insufficient alveolar gas exchange capacity is a major contributor to lung disease. During lung development, a population of distal epithelial progenitors first produce bronchiolar-fated and subsequently alveolar-fated progeny. The mechanisms controlling this bronchiolar-to-alveolar developmental tr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Development
Hauptverfasser: Laresgoiti, Usua, Nikolić, Marko Z., Rao, Chandrika, Brady, Jane L., Richardson, Rachel V., Batchen, Emma J., Chapman, Karen E., Rawlins, Emma L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087639/
https://ncbi.nlm.nih.gov/pubmed/27578791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.134023
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