A novel small molecule that disrupts a key event during the oocyte-to-embryo transition in C. elegans

The complex cellular events that occur in response to fertilization are essential for mediating the oocyte-to-embryo transition. Here, we describe a comprehensive small-molecule screen focused on identifying compounds that affect early embryonic events in Caenorhabditis elegans. We identify a single...

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Bibliografiske detaljer
Udgivet i:Development
Main Authors: Weicksel, Steven E., Mahadav, Assaf, Moyle, Mark, Cipriani, Patricia G., Kudron, Michelle, Pincus, Zachary, Bahmanyar, Shirin, Abriola, Laura, Merkel, Janie, Gutwein, Michelle, Fernandez, Anita G., Piano, Fabio, Gunsalus, Kristin C., Reinke, Valerie
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087616/
https://ncbi.nlm.nih.gov/pubmed/27510972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.140046
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