A novel small molecule that disrupts a key event during the oocyte-to-embryo transition in C. elegans

The complex cellular events that occur in response to fertilization are essential for mediating the oocyte-to-embryo transition. Here, we describe a comprehensive small-molecule screen focused on identifying compounds that affect early embryonic events in Caenorhabditis elegans. We identify a single...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Weicksel, Steven E., Mahadav, Assaf, Moyle, Mark, Cipriani, Patricia G., Kudron, Michelle, Pincus, Zachary, Bahmanyar, Shirin, Abriola, Laura, Merkel, Janie, Gutwein, Michelle, Fernandez, Anita G., Piano, Fabio, Gunsalus, Kristin C., Reinke, Valerie
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087616/
https://ncbi.nlm.nih.gov/pubmed/27510972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.140046
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