A novel small molecule that disrupts a key event during the oocyte-to-embryo transition in C. elegans

The complex cellular events that occur in response to fertilization are essential for mediating the oocyte-to-embryo transition. Here, we describe a comprehensive small-molecule screen focused on identifying compounds that affect early embryonic events in Caenorhabditis elegans. We identify a single...

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Vydáno v:Development
Hlavní autoři: Weicksel, Steven E., Mahadav, Assaf, Moyle, Mark, Cipriani, Patricia G., Kudron, Michelle, Pincus, Zachary, Bahmanyar, Shirin, Abriola, Laura, Merkel, Janie, Gutwein, Michelle, Fernandez, Anita G., Piano, Fabio, Gunsalus, Kristin C., Reinke, Valerie
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087616/
https://ncbi.nlm.nih.gov/pubmed/27510972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.140046
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