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The Role of Activin A and B and the Benefit of Follistatin Treatment in Renal Ischemia-Reperfusion Injury in Mice

BACKGROUND: Activins, members of the TGF-β superfamily, are key drivers of inflammation and are thought to play a significant role in ischemia-reperfusion injury (IRI), a process inherent to renal transplantation that negatively impacts early and late allograft function. Follistatin (FS) is a protei...

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Vydáno v:Transplant Direct
Hlavní autoři: Fang, Doreen Y.P., Lu, Bo, Hayward, Susan, de Kretser, David M., Cowan, Peter J., Dwyer, Karen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087569/
https://ncbi.nlm.nih.gov/pubmed/27830181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000000601
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