Regulation of Ca2+ signaling in transgenic mouse cardiac myocytes overexpressing calsequestrin.

To probe the physiological role of calsequestrin in excitation-contraction coupling, transgenic mice overexpressing cardiac calsequestrin were developed. Transgenic mice exhibited 10-fold higher levels of calsequestrin in myocardium and survived into adulthood, but had severe cardiac hypertrophy, wi...

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Hlavní autoři: Jones, L R, Suzuki, Y J, Wang, W, Kobayashi, Y M, Ramesh, V, Franzini-Armstrong, C, Cleemann, L, Morad, M
Médium: Artigo
Jazyk:Inglês
Vydáno: 1998
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC508716/
https://ncbi.nlm.nih.gov/pubmed/9525981
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