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Lipid-based surface engineering of PLGA nanoparticles for drug and gene delivery applications

The use of poly(lactic-co-glycolic acid) (PLGA)-based nanocarriers presents several major challenges, including their synthetic hydrophobic surface, low transfection efficiency, short circulation half-life, and nonspecific tissue distribution. Numerous engineering strategies have been employed to ov...

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Detalhes bibliográficos
Publicado no:Biomater Res
Main Authors: Bose, Rajendran JC, Lee, Soo-Hong, Park, Hansoo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087123/
https://ncbi.nlm.nih.gov/pubmed/27807476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40824-016-0081-3
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