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Correction of renal tubular acidosis in carbonic anhydrase II-deficient mice with gene therapy.

Carbonic anhydrase II (CAII) deficiency in humans is associated with a syndrome of renal tubular acidosis, osteopetrosis, and cerebral calcification. A strain of mice of CAII deficiency due to a point mutation also manifests renal tubular acidosis. We report here that retrograde injection of cationi...

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Pubblicato in:J Clin Invest
Autori principali: Lai, L W, Chan, D M, Erickson, R P, Hsu, S J, Lien, Y H
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1998
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508709/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9525974/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI1694
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