Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.

The canalicular (apical) membrane of the hepatocyte contains an ATP-dependent transport system for organic anions, known as the multispecific organic anion transporter (cMOAT). The deduced amino acid sequence of cMOAT is 49% identical to that of the human multidrug resistance- associated protein (MR...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Evers, R, Kool, M, van Deemter, L, Janssen, H, Calafat, J, Oomen, L C, Paulusma, C C, Oude Elferink, R P, Baas, F, Schinkel, A H, Borst, P
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1998
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508708/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9525973/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119886
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