Mutational landscape of uterine and ovarian carcinosarcomas implicates histone genes in epithelial–mesenchymal transition

Carcinosarcomas (CSs) of the uterus and ovary are highly aggressive neoplasms containing both carcinomatous and sarcomatous elements. We analyzed the mutational landscape of 68 uterine and ovarian CSs by whole-exome sequencing. We also performed multiregion whole-exome sequencing comprising two carc...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Proc Natl Acad Sci U S A
المؤلفون الرئيسيون: Zhao, Siming, Bellone, Stefania, Lopez, Salvatore, Thakral, Durga, Schwab, Carlton, English, Diana P., Black, Jonathan, Cocco, Emiliano, Choi, Jungmin, Zammataro, Luca, Predolini, Federica, Bonazzoli, Elena, Bi, Mark, Buza, Natalia, Hui, Pei, Wong, Serena, Abu-Khalaf, Maysa, Ravaggi, Antonella, Bignotti, Eliana, Bandiera, Elisabetta, Romani, Chiara, Todeschini, Paola, Tassi, Renata, Zanotti, Laura, Odicino, Franco, Pecorelli, Sergio, Donzelli, Carla, Ardighieri, Laura, Facchetti, Fabio, Falchetti, Marcella, Silasi, Dan-Arin, Ratner, Elena, Azodi, Masoud, Schwartz, Peter E., Mane, Shrikant, Angioli, Roberto, Terranova, Corrado, Quick, Charles Matthew, Edraki, Babak, Bilgüvar, Kaya, Lee, Moses, Choi, Murim, Stiegler, Amy L., Boggon, Titus J., Schlessinger, Joseph, Lifton, Richard P., Santin, Alessandro D.
التنسيق: Artigo
اللغة:Inglês
منشور في: National Academy of Sciences 2016
الموضوعات:
Biological Sciences
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087050/
https://ncbi.nlm.nih.gov/pubmed/27791010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614120113
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